Biotinylated Human IL-12B&IL-12A Heterodimer Protein, His,Avitag?&Flag Tag [IL2-H8210]

サプライヤー: AcroBioSystems
カタログNo.: IL2-H8210
製品名称: Biotinylated Human IL-12B&IL-12A Heterodimer Protein, His,Avitag?&Flag Tag
タンパク質名: IL-12B & IL-12A
Species: Human
HOST: HEK293

Synonyms	-
Characteristics	Biotinylated Human IL-12B&IL-12A Heterodimer Protein, His,Avitag&Flag Tag is produced by co-expression of IL-12B and IL-12A, has a calculated MW of 38.3 kDa (IL-12B) and 23.8 kDa (IL-12A). Subunit IL-12B is fused with a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag?) and subunit IL-12A is fused with flag tag at the C-terminus. The reducing (R) heterodimer protein migrates as 40-50 kDa (IL12B) and 32-35 kDa (IL12A) respectively due to glyosylation.
Endotoxin Level	1.0 EU per μg
Purity	90%
Description	Interleukin 12 (IL12) is also known as p70, and is an interleukin that is naturally produced by dendritic cells, macrophages and human B-lymphoblastoid cells (NC-37) in response to antigenic stimulation.IL12 is a heterodimeric cytokine, containing IL-12A (p35) and IL-12B (p40). IL-12 is involved in the differentiation of naive T cells into Th1 cells. It is known as a T cell-stimulating factor, which can stimulate the growth and function of T cells. It stimulates the production of IFN-γ and TNF-α from T cells and NK cells, and reduces IL-4 mediated suppression of IFN-γ. IL-12 plays an important role in the activities of natural killer cells and T lymphocytes. IL-12 also has anti-angiogenic activity, which means it can block the formation of new blood vessels.
Reference	-
URL	https://www.acrobiosystems.com/P3534-Biotinylated-Human-IL-12BIL-12A-Heterodimer-Protein-HisAvitag%E2%84%A2Flag-Tag.html

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