Cynomolgus IL-31 Protein, His Tag, Ultra Low Endotoxin (MALS verified) [IL1-C52H3]

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サプライヤー: AcroBioSystems
カタログNo.: IL1-C52H3
製品名称: Cynomolgus IL-31 Protein, His Tag, Ultra Low Endotoxin (MALS verified)
タンパク質名: IL-31
Species: Cynomolgus
HOST: HEK293

Synonyms	-
Characteristics	This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 17.3 kDa. The protein migrates as 21-24 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	0.0005 EU per μg
Purity	90%
Description	IL-31 is an inflammatory cytokine that helps trigger cell-mediated immunity against pathogens. Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. It has also been identified as a major player in a number of chronic inflammatory diseases, including atopic dermatitis. May function in skin immunity. IL-31 is produced by a variety of cells, namely type 2 helper (TH2) T-cells. IL-31 sends signals through a receptor complex made of IL-31RA and oncostatin M receptor β (OSMRβ) expressed in immune and epithelial cells. These signals activate three pathways: ERK1/2 MAP kinase, PI3K/AKT, and JAK1/2 signaling pathways.
Reference	-
URL	https://www.acrobiosystems.com/products/protein/il-31-cynomolgus-il1-c52h3

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