リコンビナントタンパク質
ACROBiosystems社 プロダクトリスト:Recombinant Protein
- サプライヤー
- AcroBioSystems
- カタログNo.
- IGA-M8210
- 製品名称
- Biotinylated Mouse IgG2a Fc Protein, Avitag? (MALS verified)
- タンパク質名
- IgG2a Fc
- Species
- Mouse
- HOST
- HEK293
Overview
Synonyms | - |
---|---|
Characteristics | This protein carries an Avi tag (Avitag?) at the C-terminus. The protein has a calculated MW of 28.2 kDa. The protein migrates as 32-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Endotoxin Level | 1.0 EU per μg |
Purity | 95% |
Description | Immunoglobulin G2 (IgG2) is a member of many immunoglobulin G developed and secreted by effective B cells. In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment. The Fc segment bears a highly conserved N-glycosylation site. There are two members of IgG2: IgG2a and IgG2b. It was found that IgG2a was superior to IgG1 in activating complement. The glycosylation of the circulating immunoglobulin-γ (IgG) antibody molecules changes in rheumatoid arthritis. |
Reference | - |
URL | https://www.acrobiosystems.com/P2071-Biotinylated-Mouse-IgG2a-Fc-Protein-Avitag%E2%84%A2-%28MALS-verified%29.html |