リコンビナントタンパク質
ACROBiosystems社 プロダクトリスト:Recombinant Protein
- サプライヤー
- AcroBioSystems
- カタログNo.
- IGA-M5207
- 製品名称
- Mouse IgG2a Fc Protein, Tag Free (MALS verified)
- タンパク質名
- IgG2a Fc
- Species
- Mouse
- HOST
- HEK293
Overview
Synonyms | - |
---|---|
Characteristics | This protein carries no "tag". The protein has a calculated MW of 26.4 kDa. As a result of glycosylation, the protein migrates as 30-35 kDa under reducing (R) condition, and 55-60 kDa under non-reducing (NR) condition (SDS-PAGE). |
Endotoxin Level | 1.0 EU per μg |
Purity | 90% |
Description | Immunoglobulin G2 (IgG2) is a member of many immunoglobulin G developed and secreted by effective B cells. In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment. The Fc segment bears a highly conserved N-glycosylation site. There are two members of IgG2: IgG2a and IgG2b. It was found that IgG2a was superior to IgG1 in activating complement. The glycosylation of the circulating immunoglobulin-γ (IgG) antibody molecules changes in rheumatoid arthritis. |
Reference | - |
URL | https://www.acrobiosystems.com/P703-Mouse-IgG2a-Fc-Protein-Tag-Free-%28MALS-verified%29.html |