Biotinylated Human IGFBP-7 Protein, His,Avitag? (MALS verified) [IG7-H82Q9]

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Synonyms	-
Characteristics	This protein carries a polyhistidine tag at the N-terminus, followed by an Avi tag (Avitag?). The protein has a calculated MW of 29.8 kDa. The protein migrates as 34-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	N/A
Purity	95%
Description	Insulin-like growth factor-binding protein 7 (IGFBP7) is also known as IGFBP-rP1, MAC25 protein, PGI2-stimulating factor, prostacyclin-stimulating factor and tumor-derived adhesion factor, which contains one Ig-like C2-type (immunoglobulin-like) domain, one IGFBP N-terminal domain and one Kazal-like domain. The major function of IGFBP7 is the regulation of availability of insulin-like growth factors (IGFs) in tissue as well as in modulating IGF binding to its receptors. IGFBP7 binds to IGF with high affinity except for IGF-I and IGF-II.IGFBP7 also stimulates cell adhesion. Furthermore, IGFBP7 is implicated in some cancers.
Reference	-
URL	https://www.acrobiosystems.com/products/protein/igfbp-7-human-ig7-h82q9

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