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ACROBiosystems社 プロダクトリスト:Recombinant Protein

サプライヤー
AcroBioSystems
カタログNo.
IG1-H8213
製品名称
Biotinylated Human IgG1 Fc protein, Avi Tag (Avitag)
タンパク質名
IgG Fc
Species
Human
HOST
HEK293
25ug: 74,000円
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500ug: 347,000円
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Overview

Synonyms IgG Fc
Characteristics This protein carries an Avi tag at the C-terminus. The protein has a calculated MW of 28.4 kDa. The protein migrates as 36-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level Less than 1.0 EU per μg by the LAL method.
Purity >95% as determined by SDS-PAGE.
Description Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.
Reference (1) Medinger M, Tzankov A,et al.( 2010), J Clin Immunol. 30 Suppl 1:S9-14.
URL https://www.acrobiosystems.com/P2388-Biotinylated-Human-IgG-Fc-Protein-Avi-Tag.html

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