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- サプライヤー
- AcroBioSystems
- カタログNo.
- HLP-HP2Hc
- 製品名称
- PE-Labeled Human HLA-A*24:02&B2M&p53 (TYSPALNKMF) Tetramer Protein
- タンパク質名
- HLA-A*2402 & B2M & p53 (TYSPALNKMF)
- Species
- Human
- HOST
- HEK293
Overview
| Synonyms | - |
|---|---|
| Characteristics | PE-Labeled Human HLA-A*24:02&B2M&p53 (TYSPALNKMF) Tetramer Protein is assembled by biotinylated monomer (HLP-H82Eb) and PE-labeled streptavidin. Biotinylated Human HLA-A*24:02&B2M&p53 (TYSPALNKMF) Complex Protein is produced by co-expression of HLA and B2M loaded with p53 peptide. Biotinylated Human HLA-A*24:02&B2M&p53 (TYSPALNKMF) Complex Protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag?). |
| Endotoxin Level | N/A |
| Purity | 90% |
| Description | TP53 has been recognized as a tumor suppressor. 50% of cancers carry a TP53 mutation while many others affect other pathway components. High-copy numbers of WT p53 peptide-MHC class I complexes were detected on tumor cells as compared to low copies on normal cells. The Human HLA-A*0201 p53 (GLAPPQHLIRV) complex protein is a complex of HLA-A*0201 of the MHC Class I, B2M, and GLAPPQHLIRV peptide of the p53. |
| Reference | - |
| URL | https://www.acrobiosystems.com/products/protein/hla-a-2402-b2m-p53-tyspalnkmf-human-hlp-hp2hc |
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