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タンパク質カタログ
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- サプライヤー
- AcroBioSystems
- カタログNo.
- HLP-H82Ee
- 製品名称
- Human HLA-A*02:01&B2M&p53 (HMTEVVRRC) Tetramer Protein (MALS verified)
- タンパク質名
- HLA-A*0201 & B2M & p53 (HMTEVVRRC)
- Species
- Human
- HOST
- HEK293
Overview
| Synonyms | - |
|---|---|
| Characteristics | Human HLA-A*02:01&B2M&p53 (HMTEVVRRC) Tetramer Protein is assembled by biotinylated monomer and streptavidin. Biotinylated HLA-A*02:01&B2M&p53 (HMTEVVRRC) Complex Protein is produced by co-expression of HLA-A*02:01 and B2M loaded with p53 peptide. Biotinylated HLA-A*02:01&B2M&p53 (HMTEVVRRC) Complex Protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag?). This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag?). The protein has a calculated MW of 36.3 kDa and 13.3 kDa and 11.7 kDa. The protein migrates as 41-45 kDa, 12 kDa and 10 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Endotoxin Level | N/A |
| Purity | 95% |
| Description | TP53 has been recognized as a tumor suppressor. 50% of cancers carry a TP53 mutation while many others affect other pathway components. High-copy numbers of WT p53 peptide-MHC class I complexes were detected on tumor cells as compared to low copies on normal cells. The Human HLA-A*0201 p53 (HMTEVVRRC) complex protein is a complex of HLA-A*0201 of the MHC Class I, B2M, and HMTEVVRRC peptide of the p53. |
| Reference | - |
| URL | https://www.acrobiosystems.com/products/protein/hla-a-0201-b2m-p53-hmtevvrrc-human-hlp-h82ee |
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