Biotinylated Chimeric HLA-A*02:01 (H-2Kb α3)&B2M&GP100 (YLEPGPVTA) Complex Protein (Monomer, MALS verified) [HLG-H82E9]

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サプライヤー: AcroBioSystems
カタログNo.: HLG-H82E9
製品名称: Biotinylated Chimeric HLA-A*02:01 (H-2Kb α3)&B2M&GP100 (YLEPGPVTA) Complex Protein (Monomer, MALS verified)
タンパク質名: Chimeric HLA-A*0201 (H-2Kb α3) & B2M & GP100(YLEPGPVTA)
Species: Human & Mouse
HOST: HEK293

Synonyms	-
Characteristics	Biotinylated Chimeric HLA-A*02:01 (H-2Kb α3)&B2M&GP100 (YLEPGPVTA) Complex Protein is produced by co-expression of HLA, H-2Kb and B2M loaded with GP100 peptide. This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag?). The protein has a calculated MW of 50.3 kDa. The protein migrates as 50-53 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	N/A
Purity	90%
Description	Glycoprotein 100, is also well known as gp100 and Melanocyte protein PMEL. This antigen is a melanocyte-specific type I transmembrane glycoprotein and composed of 661 amino acids. Glycoprotein 100 is related to the tumor regression in metastatic melanoma patients after adoptive therapy, by which its epitopes being recognized by tumor lymphocytes and T-cells. The gp100280?288(YLEPGPVTA) was originally shown to be recognized by HLA-A0201 tumor-infiltrating lymphocytes from melanoma patients, and therefore it is widely been studied in TCR -T studies. The Human HLA-A0201 Mouse H-2Kb gp100 (YLEPGPVTA) complex protein is a complex of HLA-A*0201 & H-2Kb of the MHC Class I, hB2M and YLEPGPVTA peptide of the gp100.
Reference	-
URL	https://www.acrobiosystems.com/products/protein/chimeric-hla-a-0201-h-2kb-α3-b2m-gp100-ylepgpvta-human-mouse-hlg-h82e9

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