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タンパク質カタログ
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- サプライヤー
- AcroBioSystems
- カタログNo.
- HLD-H52H4
- 製品名称
- Human HLA-A*11:01&B2M&KRASG12D (VVGADGVGK) Complex Protein (Monomer, MALS verified)
- タンパク質名
- HLA-A*1101 & B2M & KRASG12D (VVGADGVGK)
- Species
- Human
- HOST
- HEK293
Overview
| Synonyms | - |
|---|---|
| Characteristics | Human HLA-A*11:01&B2M&KRASG12D (VVGADGVGK) Complex Protein is produced by co-expression of HLA and B2M loaded with KRASG12D peptide. This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 36.0 kDa and 11.7 kDa. The protein migrates as 41-45 kDa and 14 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Endotoxin Level | 1.0 EU per μg |
| Purity | 90% |
| Description | The Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) oncogene plays a critical role in the initiation and maintenance of pancreatic tumors and its signaling network represents a major target for therapeutic intervention. The Alex Fluor labeled Human HLA-A*1101 KRASG12D (VVGADGVGK) complex protein is a complex of HLA-A*1101 of the MHC Class I, B2M, and VVGADGVGK peptide of the KRASG12D. |
| Reference | - |
| URL | https://www.acrobiosystems.com/products/protein/hla-a-1101-b2m-krasg12d-vvgadgvgk-human-hld-h52h4 |
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