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- サプライヤー
- AcroBioSystems
- カタログNo.
- HLB-H82E4
- 製品名称
- Biotinylated Human HLA-A*02:01&B2M&insB (HLVEALYLV) Complex Protein (Monomer, MALS verified)
- タンパク質名
- HLA-A*0201 & B2M & insB (HLVEALYLV)
- Species
- Human
- HOST
- HEK293
Overview
| Synonyms | - |
|---|---|
| Characteristics | Biotinylated Human HLA-A*02:01&B2M&insB (HLVEALYLV) Complex Protein is produced by co-expression of HLA-A*0201 and B2M loaded with insB peptide. This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag?). The protein has a calculated MW of 36.4 kDa and 13.8 kDa. The protein migrates as 40-43 kDa and 12 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Endotoxin Level | N/A |
| Purity | 90% |
| Description | Insulin is a heterodimer formed by connecting the A chain (21 amino acids) and B chain (30 amino acids) through two disulfide bonds (A7-B7, A20-B19). Its three-dimensional structure presents a compact spherical conformation. HLVEALYLV is located at amino acids 10-18 of the B chain, and stabilizes the binding interface between insulin and IR through hydrophobic interactions. By regulating the conformation of insulin, it affects its interaction with downstream signaling molecules. The Human HLA-A*0201 & B2M & insB (HLVEALYLV) complex protein is a complex of HLA-A*0201 of the MHC Class I, B2M, and HLVEALYLV peptide of the insB. |
| Reference | - |
| URL | https://www.acrobiosystems.com/products/protein/hla-a-0201-b2m-insb-hlvealylv-human-hlb-h82e4 |
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