タンパク質、抗体、アッセイキット
タンパク質カタログ
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- サプライヤー
- AcroBioSystems
- カタログNo.
- HL4-HA2E3
- 製品名称
- APC-Labeled Human HLA-A*02:01&B2M&MAGE-A4 (GVYDGREHTV) Tetramer Protein
- タンパク質名
- HLA-A*0201 & B2M &MAGE-A4 (GVYDGREHTV)
- Species
- Human
- HOST
- HEK293
Overview
| Synonyms | - |
|---|---|
| Characteristics | APC-Labeled Human HLA-A*02:01&B2M&MAGE-A4 (GVYDGREHTV) Tetramer Protein is assembled by biotinylated monomer and APC-labeled streptavidin. Biotinylated Human HLA-A*02:01&B2M&MAGE-A4 (GVYDGREHTV) Complex Protein s produced by co-expression of HLA-A*02:01 and B2M loaded with MAGE-A4 peptide. Biotinylated Human HLA-A*02:01&B2M&MAGE-A4 (GVYDGREHTV) Complex Protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag?). This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag?). The protein has a calculated MW of 36.3 kDa and 11.7 kDa. |
| Endotoxin Level | N/A |
| Purity | N/A |
| Description | MHC Class I molecules are expressed on nearly all nucleated cells and present peptides to cytotoxic T-cells (CD8+) to survey for infected or cancerous cells. MAGE-A4 is normally silent in adult tissues (except testes and placenta) but is aberrantly expressed in various tumors (e.g., melanoma, lung cancer), making it a prime target for cancer immunotherapy, including T-cell therapies and vaccines. |
| Reference | - |
| URL | https://www.acrobiosystems.com/products/protein/hla-a-0201-b2m-mage-a4-gvydgrehtv-human-hl4-ha2e3 |

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