Unconjugated Human HLA-A*01:01&B2M&MAGEA3 (EVDPIGHLY) Complex Protein (Monomer, MALS verified) [HL3-H52E3]

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サプライヤー: AcroBioSystems
カタログNo.: HL3-H52E3
製品名称: Unconjugated Human HLA-A*01:01&B2M&MAGEA3 (EVDPIGHLY) Complex Protein (Monomer, MALS verified)
タンパク質名: HLA-A*0101 & B2M & MAGEA3 (EVDPIGHLY)
Species: Human
HOST: HEK293

Synonyms	-
Characteristics	Unconjugated Human HLA-A01:01&B2M&MAGEA3 (EVDPIGHLY) Complex Protein is produced by co-expression of HLA-A01:01 and B2M loaded with MAGEA3 peptide. This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag?), and it is not biotinylated. The protein has a calculated MW of 36.0 kDa and 13.8 kDa. The protein migrates as 40-43 kDa and 12 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	N/A
Purity	90%
Description	The HLA-A*01:01 allele is a prevalent human MHC class I variant, and its peptide-binding specificity determines the immune response in individuals carrying this allele. MAGEA3 is a member of the Melanoma-Associated Antigen family, characterized by its restricted expression in normal tissues (primarily testes and placenta) but frequent re-expression in various tumors, such as melanoma, lung cancer, and others.
Reference	-
URL	https://www.acrobiosystems.com/products/protein/hla-a-0101-b2m-magea3-evdpighly-human-hl3-h52e3

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