Biotinylated Human HLA-A*24:02&B2M&NY-ESO-1 (LLMWITQCF) Complex Protein (Monomer, MALS verified) [HL1-H82E3]

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サプライヤー: AcroBioSystems
カタログNo.: HL1-H82E3
製品名称: Biotinylated Human HLA-A*24:02&B2M&NY-ESO-1 (LLMWITQCF) Complex Protein (Monomer, MALS verified)
タンパク質名: HLA-A*2402 & B2M & NY-ESO-1 (LLMWITQCF)
Species: Human
HOST: HEK293

Synonyms	-
Characteristics	Biotinylated Human HLA-A*24:02&B2M&NY-ESO-1 (LLMWITQCF) Complex Protein is produced by co-expression of HLA and B2M loaded with NY-ESO-1 peptide. This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag?). The protein has a calculated MW of 35.8 kDa and 11.7 kDa. The protein migrates as 38-42 kDa and <14 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	N/A
Purity	90%
Description	NY-ESO-1, which is also well-known as New York esophageal squamous cell carcinoma 1, is an efficient target for cancer immunotherapy. This antigen is a member of cancer-testis antigens (CTAs) and is highly expressed in various cancers, including melanoma, ovarian, cervical cancer, etc. Adoptive T cell therapy with HLA-A24 restricted NY-ESO-1 transduced CD8+ T cells has improved the clinical response rates and overall survival of treatment-refractory melanoma patients. The Human HLA-A2402 NY-ESO-1 (LLMWITQCF) complex protein is a complex of HLA-A2402 of the MHC Class I, B2M and LLMWITQCF peptide of the NY-ESO-1.
Reference	-
URL	https://www.acrobiosystems.com/products/protein/hla-a-2402-b2m-ny-eso-1-llmwitqcf-human-hl1-h82e3

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