リコンビナントタンパク質
ACROBiosystems社 プロダクトリスト:Recombinant Protein
- サプライヤー
- AcroBioSystems
- カタログNo.
- HL0-H82E5
- 製品名称
- Biotinylated Human HLA-E*01:03&B2M&CMV UL40 (VMAPRTLLL) Complex Protein (Monomer, MALS verified)
- タンパク質名
- HLA-E*0103 & B2M & CMV UL40 (VMAPRTLLL)
- Species
- Human
- HOST
- HEK293
Overview
Synonyms | - |
---|---|
Characteristics | Biotinylated Human HLA-E*01:03&B2M&CMV UL40 (VMAPRTLLL) Complex Protein is produced by co-expression of HLA and B2M loaded with CMV UL40 peptide. This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag?). The protein has a calculated MW of 36.2 kDa and 13.8 kDa. The protein migrates as 40-43 kDa and 12 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Endotoxin Level | 1.0 EU per μg |
Purity | 95% |
Description | HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. |
Reference | - |
URL | https://www.acrobiosystems.com/P7286-Biotinylated-Human-HLA-E%2A01%3A03B2MCMV-UL40-%28VMAPRTLLL%29-Complex-Protein-%28Monomer-MALS-verified%29.html |