Human Her2 & ErbB3 Protein, Fc Tag&Fc Tag (MALS verified) [HE2-H5254]

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Synonyms	-
Characteristics	Human Her2 & ErbB3 Protein, Fc Tag&Fc Tag, produced by co-expression of HER2 and ErbB3, has a calculated MW of 95.9 kDa (HER2) and 94.9 kDa (ErbB3). Subunit HER2 is fused with a human IgG1 Fc fragment at the C-terminus and subunit ErbB3 is fused with a human IgG1 Fc fragment at the C-terminus. The protein migrates as 110-130 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	1.0 EU per μg
Purity	90%
Description	The Human Epidermal Growth Factor Receptor 2 (HER2) and HER3 form a potent pro-oncogenic heterocomplex upon binding of growth factor neuregulin-1β (NRG1β). The HER2/HER3 extracellular dimer dynamics likely have important implications for modulating receptor activity.
Reference	-
URL	https://www.acrobiosystems.com/products/protein/her2-erbb3-human-he2-h5254

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