Human Glypican 3 / GPC3 (S495A, S509A) Protein, His Tag [GP3-H52H8]

Synonyms	-
Characteristics	This protein carries a polyhistidine tag at the C-terminus. This protein contains a furin-like convertase cleavage site, 355-RQYR-358, and will be partially processed into N and C-terminal fragment with calculated MW of 38.1 kDa and 24.5 kDa respectively. The protein migrates as 28-32 kDa, 42-45 kDa and 65-75 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	0.1 EU per μg
Purity	90%
Description	Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.
Reference	-
URL	https://www.acrobiosystems.com/P4949-Human-Glypican-3--GPC3-%28S495A-S509A%29-Protein-His-Tag.html

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