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- サプライヤー
- AcroBioSystems
- カタログNo.
- GP0-V52H3
- 製品名称
- Human immunodeficiency virus 1 gp140 Protein, His Tag (MALS verified)
- タンパク質名
- Envelope glycoprotein gp140/gp140 (HIV)
- Species
- Human immunodeficiency virus 1 (HIV-1)
- HOST
- HEK293
Overview
| Synonyms | - |
|---|---|
| Characteristics | This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 53.7 kDa & 19.3 kDa. The protein migrates as 110-120 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Endotoxin Level | 1.0 EU per μg |
| Purity | 90% |
| Description | The trimeric envelope glycoproteins (Env) that are displayed on human and simian immunodeficiency viruses (HIV and SIV, respectively) are heterodimers of the transmembrane glycoprotein (gp41) and a surface glycoprotein (gp120). The glycoproteins gp120 and gp41 are synthesized initially as a single gp160 polypeptide that is subsequently cleaved to generate the noncovalently associated gp120/gp41 complex. Soluble versions of trimeric gp140, either cleaved or uncleaved, are being developed as immunogens to elicit a protective humoral immune response against HIV-1 infection. |
| Reference | - |
| URL | https://www.acrobiosystems.com/products/protein/envelope-glycoprotein-gp140-gp140-hiv-human-immunodeficiency-virus-1-hiv-1-gp0-v52h3 |
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