Biotinylated Human GLP1R Protein, His,Avitag? (HPLC verified) [GLR-H82E3]

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Synonyms	-
Characteristics	This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag?). The protein has a calculated MW of 17.3 kDa. The protein migrates as 30-34 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	N/A
Purity	90%
Description	This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion.?This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion.?It also displays neuroprotective effects in animal models.?Polymorphisms in this gene are associated with diabetes.?The protein is an important drug target for the treatment of type 2 diabetes and stroke.
Reference	-
URL	https://www.acrobiosystems.com/products/protein/glp1r-human-glr-h82e3

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