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ACROBiosystems社 プロダクトリスト:Recombinant Protein

サプライヤー
AcroBioSystems
カタログNo.
GIR-C5255
製品名称
Rhesus macaque GITR / TNFRSF18 Protein, Fc Tag
タンパク質名
GITR
Species
Rhesus macaque
HOST
HEK293
100ug: 74,000円
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1mg: 416,000円
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Overview

Synonyms AITR,GITR,TNFRSF18,CD357
Characteristics This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 41.3 kDa. As a result of glycosylation, the protein migrates as 48 kDa under reducing (R) condition, and 85 kDa under non-reducing (NR) condition (SDS-PAGE).
Endotoxin Level Less than 1.0 EU per μg by the LAL method.
Purity >95% as determined by SDS-PAGE.
Description Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.
Reference (1) Gurney A.L., et al., 1999, Curr. Biol. 9:215-218.
(2) Park MS., et al., 2007, Yonsei Med J 48 (5): 839-46.
URL https://www.acrobiosystems.com/P2172-Rhesus-macaque-GITR--TNFRSF18-Protein-Fc-Tag.html

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