Biotinylated Human Growth Hormone R Protein, Fc,Avitag? (MALS verified) [GHR-H82F3]

サプライヤー: AcroBioSystems
カタログNo.: GHR-H82F3
製品名称: Biotinylated Human Growth Hormone R Protein, Fc,Avitag? (MALS verified)
タンパク質名: Growth Hormone R
Species: Human
HOST: HEK293

Synonyms	-
Characteristics	This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag?). The protein has a calculated MW of 55 kDa. The protein migrates as 65-90 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	1.0 EU per μg
Purity	90%
Description	Growth hormone receptor (GHR) is also known as somatotropin receptor, growth hormone-binding protein (GHBR), which belongs to the type I cytokine receptor family or Type 1 subfamily. GHR contains one fibronectin type-III domain. GHR / GHBR is expressed in various tissues with high expression in liver and skeletal muscle. The soluble form (GHBP) is produced by phorbol ester-promoted proteolytic cleavage at the cell surface (shedding) by ADAM17/TACE. GHR is receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway. The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.
Reference	-
URL	https://www.acrobiosystems.com/P6131-Biotinylated-Human-Growth-Hormone-R-Protein-FcAvitag%E2%84%A2-%28MALS-verified%29.html

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