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タンパク質カタログ
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- サプライヤー
- AcroBioSystems
- カタログNo.
- GDF-M5245
- 製品名称
- Mouse GDNF / ATF Protein, His Tag (MALS verified)
- タンパク質名
- GDNF
- Species
- Mouse
- HOST
- HEK293
Overview
| Synonyms | - |
|---|---|
| Characteristics | This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 17.0 kDa. The protein migrates as 16 kDa, 18 kDa and 22-24 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Endotoxin Level | 0.1 EU per μg |
| Purity | 90% |
| Description | Glial?cell?line-derived?neurotrophic?factor?(GDNF) is a glycosylated, disulfide-bonded homodimer that is a distantly related member of the transforming growth factor-beta (TGF-beta) superfamily. It potently promotes the survival of of peripheral and central neurons. It signals through GFRα receptors, particularly GFRα1. Neuronal subpopulations that have been shown to be affected by GDNF include motoneurons, midbrain dopaminergic neurons, Purkinje cells and sympathetic neurons. |
| Reference | - |
| URL | https://www.acrobiosystems.com/products/protein/gdnf-mouse-gdf-m5245 |
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