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タンパク質カタログ
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- サプライヤー
- AcroBioSystems
- カタログNo.
- GD8-H5343
- 製品名称
- Human latent GDF-8 Protein, His Tag (MALS verified)
- タンパク質名
- GDF-8
- Species
- Human
- HOST
- CHO
Overview
| Synonyms | - |
|---|---|
| Characteristics | This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 42.0 kDa. The protein migrates as 10-11 kDa and 38-40 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE). |
| Endotoxin Level | 1.0 EU per μg |
| Purity | 90% |
| Description | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals. [provided by RefSeq, Jul 2016] |
| Reference | - |
| URL | https://www.acrobiosystems.com/products/protein/gdf-8-human-gd8-h5343 |
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