ACROBiosystems社 プロダクトリスト：Recombinant Protein
- Human Galectin-4 / LGALS4 / L36LBP Protein, His tag
|Synonyms||LGALS4,L36LBP,Gal-4,Antigen NY-CO-27,Lactose-binding lectin 4|
|Characteristics||This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 38.1 kDa. The protein migrates as 40-44 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.|
|Endotoxin Level||Less than 1.0 EU per μg by the LAL method.|
|Purity||>95% as determined by SDS-PAGE.|
|Description||Galectin-4 (Gal-4), also known as L36LBP (L-36 lactose-binding protein). The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin-4 expression is concentrated within microvilli in the gastrointestinal epithelium, where it can interact with CD3 and bind activated T cells in the lamina propria during intestinal inflammation. LGALS4 is an S-type lectin that is strongly underexpressed in colorectal cancer.|
|Reference||(1) Barondes SH., et al., 1994, J. Biol. Chem. 269 (33): 20807-20810.
(2) Yang, RY., et al., 2008, Expert Rev. Mol. Med. 10: e17.
(3) Ideo H., et al., 2007, J. Biol. Chem. 282 (29): 21081-21089.