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ACROBiosystems社 プロダクトリスト:Recombinant Protein

サプライヤー
AcroBioSystems
カタログNo.
GA1-H5543
製品名称
Human GAD1 / GAD67 Protein, His Tag
タンパク質名
GAD1
Species
Human
HOST
InsectCells
100ug: 98000円
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1mg: 646800円
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Overview

Synonyms -
Characteristics This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 68.8 kDa. The protein migrates as 66 kDa, 90 kDa and >116 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level 1.0 EU per μg
Purity 85%
Description Glutamate?decarboxylase?or?glutamic?acid?decarboxylase?(GAD)?is?an?enzyme?that?catalyzes?the?decarboxylation?of?glutamate?to?gamma-aminobutyric?acid?(GABA), the major inhibitory transmitter in higher brain regions, and putative paracrine hormone in pancreatic islets.?GAD?uses?pyridoxal-phosphate?(PLP)?as?a?cofactor.Two molecular forms of GAD (65 kDa and 67 kDa) are highly conserved and both are expressed in the CNS, pancreatic islet cells, testis, oviduct and ovary. The isoforms are regionally distributed cytoplasmically in the brains of rats and mice. GAD65 is an ampiphilic, membrane-anchored protein (585 a.a.), and is responsible for vesicular GABA production. GAD67 is cytoplasmic (594 a.a.), and seems to be responsible for significant cytoplasmic GABA production.
Reference -
URL https://www.acrobiosystems.com/P5554-Human-GAD1--GAD67-Protein-His-Tag.html

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