リコンビナントタンパク質
ACROBiosystems社 プロダクトリスト:Recombinant Protein
- サプライヤー
- AcroBioSystems
- カタログNo.
- FUS-H5144
- 製品名称
- Human FUS Protein, His Tag
- タンパク質名
- FUS
- Species
- Human
- HOST
- E. coli
Overview
Synonyms | - |
---|---|
Characteristics | This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 97.0 kDa. The protein migrates as 95 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE). |
Endotoxin Level | 1.0 EU per μg |
Purity | 85% |
Description | FUS (RNA-binding protein FUS) is a DNA/RNA-binding protein that plays a role in various cellular processes such as transcription regulation, RNA splicing, RNA transport, DNA repair and damage response. It binds to nascent pre-mRNAs and acts as a molecular mediator between RNA polymerase II and U1 small nuclear ribonucleoprotein thereby coupling transcription and splicing. It binds also its own pre-mRNA and autoregulates its expression; this autoregulation mechanism is mediated by non-sense-mediated decay. FUS plays a role in DNA repair mechanisms by promoting D-loop formation and homologous recombination during DNA double-strand break repair. In neuronal cells, FUS plays crucial roles in dendritic spine formation and stability, RNA transport, mRNA stability and synaptic homeostasis. |
Reference | - |
URL | https://www.acrobiosystems.com/P6674-Human-FUS-Protein-His-Tag.html |