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タンパク質カタログ
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- サプライヤー
- AcroBioSystems
- カタログNo.
- FG4-H51H3
- 製品名称
- Human FGF-4 Protein, His Tag
- タンパク質名
- FGF-4
- Species
- Human
- HOST
- E. coli
Overview
| Synonyms | - |
|---|---|
| Characteristics | This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 19.8 kDa. The protein migrates as 23-24 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE). |
| Endotoxin Level | 1.0 EU per μg |
| Purity | 90% |
| Description | Fibroblast growth factor-4 (FGF4) is expressed in embryonic stages and in adult tissues, where it plays critical roles in modulating multiple cellular functions. Fibroblast growth factor 4 (FGF4) is a multipotent growth factor and is highly expressed in various human cancers. In lung adenocarcinoma (ADC) cell lines, FGF4 could alter cell morphology, promote epithelial-mesenchymal transition-associated protein expression, and enhance cell proliferation, migration/invasion and colony initiation. In B-cell lymphoma, FGF4 secretion by cancer cells induces Jag1 expression in neighbor Endothelial cell that in turn activates Notch2 in lymphoma cells. |
| Reference | - |
| URL | https://www.acrobiosystems.com/products/protein/fgf-4-human-fg4-h51h3 |
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