Mouse FcRn / FCGRT&B2M Heterodimer Protein, His Tag&Twin-Strep Tag (MALS & BLI verified) [FCM-M52W2]

サプライヤー: AcroBioSystems
カタログNo.: FCM-M52W2
製品名称: Mouse FcRn / FCGRT&B2M Heterodimer Protein, His Tag&Twin-Strep Tag (MALS & BLI verified)
タンパク質名: FcRn (FCGRT & B2M)
Species: Mouse
HOST: HEK293

Synonyms	-
Characteristics	Mouse FCGRT&B2M Heterodimer Protein, His Tag&Twin-Strep Tag, produced by co-expression of FCGRT and B2M, has a calculated MW of 32.9 kDa (FCGRT) and 14.7 kDa (B2M). Subunit FCGRT is fused with a polyhistidine tag at the C-terminus and subunit Beta-2 microglobulin (B2M) is fused with Twin-Strep tag at the C-terminus. The reducing (R) protein migrates as 42-48 kDa (FCGRT) and 15-17 kDa (B2M) respectively due to glycosylation.
Endotoxin Level	1.0 EU per μg
Purity	95%
Description	FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51 (equivalent to FCGRT), and p14 (equivalent to beta-2-microglobulin), and forms an MHC class I-like heterodimer. Fc fragment of IgG, receptor, transporter, alpha (FCGRT) binds to the Fc region of monomeric immunoglobulins gamma and mediates the uptake of IgG from milk. FCGRT possible role in transfer of immunoglobulin G from mother to fetus. Beta-2-microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and involved in the presentation of peptide antigens to the immune system.
Reference	-
URL	https://www.acrobiosystems.com/P1737-Mouse-FcRn--FCGRTB2M-Heterodimer-Protein-His-TagTwin-Strep-Tag-%28MALS--BLI-verified%29.html

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