Human FcRn / FCGRT&B2M Heterodimer Protein, Strep Tag&Tag Free (MALS & SPR verified) [FCM-H5283]

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サプライヤー: AcroBioSystems
カタログNo.: FCM-H5283
製品名称: Human FcRn / FCGRT&B2M Heterodimer Protein, Strep Tag&Tag Free (MALS & SPR verified)
タンパク質名: FcRn (FCGRT & B2M)
Species: Human
HOST: HEK293

Synonyms	-
Characteristics	Human FCGRT&B2M Heterodimer Protein, Strep Tag&Tag Free, produced by co-expression of FCGRT and B2M, has a calculated MW of 33.8 kDa (FCGRT) and 11.7 kDa (B2M). Subunit FCGRT is fused with Strep II-tag at the C-terminus and subunit Beta-2 microglobulin (B2M) contains no tag. The reducing (R) protein migrates as 40-43 kDa (FCGRT) and 12 kDa (B2M) respectively due to glycosylation.
Endotoxin Level	1.0 EU per μg
Purity	90%
Description	FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51 (equivalent to FCGRT), and p14 (equivalent to beta-2-microglobulin), and forms an MHC class I-like heterodimer. Fc fragment of IgG, receptor, transporter, alpha (FCGRT) binds to the Fc region of monomeric immunoglobulins gamma and mediates the uptake of IgG from milk. FCGRT possible role in transfer of immunoglobulin G from mother to fetus. Beta-2-microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and involved in the presentation of peptide antigens to the immune system.
Reference	-
URL	https://www.acrobiosystems.com/products/protein/fcrn-fcgrt-b2m-human-fcm-h5283

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