Biotinylated Mouse Fc gamma RIV / CD16-2 Protein, His,Avitag? (HPLC & BLI verified) [FC4-M82E8]

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サプライヤー: AcroBioSystems
カタログNo.: FC4-M82E8
製品名称: Biotinylated Mouse Fc gamma RIV / CD16-2 Protein, His,Avitag? (HPLC & BLI verified)
タンパク質名: Fc gamma RIV / CD16-2
Species: Mouse
HOST: HEK293

Synonyms	-
Characteristics	This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag?). The protein has a calculated MW of 24.6 kDa. The protein migrates as 30-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	N/A
Purity	90%
Description	FcgR4(Low affinity immunoglobulin gamma Fc region receptor IV) is also known as CD16-2, FcgammaRIV, receptor for the Fc region of immunoglobulin gamma . Also acts as a receptor for the Fc region of immunoglobulin epsilon . Binds with intermediate affinity to both IgG2a and IgG2b . Does not display binding to IgG1 or IgG3. Plays a role in promoting bone resorption by enhancing osteoclast differentiation following binding to IgG2a. Binds with low affinity to both the a and b allotypes of IgE. Has also been shown to bind to IgE allotype a only but not to allotype b. Binding to IgE promotes macrophage-mediated phagocytosis, antigen presentation to T cells, production of proinflammatory cytokines and the late phase of cutaneous allergic reactions
Reference	-
URL	https://www.acrobiosystems.com/products/protein/fc-gamma-riv-cd16-2-mouse-fc4-m82e8

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