Cynomolgus Erythropoietin R Protein, His Tag, low endotoxin (MALS & SPR verified) [ERR-C52H3]

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サプライヤー: AcroBioSystems
カタログNo.: ERR-C52H3
製品名称: Cynomolgus Erythropoietin R Protein, His Tag, low endotoxin (MALS & SPR verified)
タンパク質名: Erythropoietin R
Species: Cynomolgus
HOST: HEK293

Synonyms	-
Characteristics	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.7 kDa. The protein migrates as 28-29 kDa and 30-33 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	0.01 EU per μg
Purity	90%
Description	This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.
Reference	-
URL	https://www.acrobiosystems.com/products/protein/erythropoietin-r-cynomolgus-err-c52h3

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