Recombinant Human SUMO2 (N-6His) [EPT277] | ナミキ商事株式会社

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サプライヤー: ELK Biotechnology
カタログNo.: EPT277
製品名称: Recombinant Human SUMO2 (N-6His)
タンパク質名: 13 KDa
Species: -
HOST: Small Ubiquitin-Related Modifier 2; SUMO-2; HSMT3; SMT3 homolog 2; SUMO-3; Sentrin-2; Ubiquitin-Like Protein SMT3A; Smt3A; SUMO2; SMT3A; SMT3H2

Synonyms	-
Characteristics	Small Ubiquitin-Related Modifier 2 (SUMO2) is an Ubiquitin-like protein that belongs to the ubiquitin family with SUMO subfamily. It is a family of small, related proteins that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation. SUMO2 can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptidebond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins.
Endotoxin Level	Less than 0.1 ng/?g (1 EU/?g) as determined by LAL test.
Purity	Greater than 95% as determined by reducing SDS-PAGE.
Description	-
Reference	-
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