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バイオ製品Bio Products

タンパク質、抗体、アッセイキット

タンパク質カタログ

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サプライヤー
ELK Biotechnology
カタログNo.
EPT274
製品名称
Recombinant Mouse TNF R1
タンパク質名
21.2 KDa
Species
-
HOST
Tumor necrosis factor receptor superfamily member 1A; Tumor necrosis factor receptor 1; Tumor necrosis factor receptor type I; Tnfr-1; Tnfr1; Tnfrsf1a;
10ug: -
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Overview

Synonyms -
Characteristics Tumor necrosis factor receptor superfamily member 1A (Tnfrsf1a) is a member of the tumor necrosis factor receptor superfamily. Tnfrsf1a is one of the major receptors for the tumor necrosis factor-alpha. It can activate the transcription factor NF-κB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the human genetic disorder called tumor necrosis factor associated periodic syndrome (TRAPS) or periodic fever syndrome
Endotoxin Level Less than 0.1 ng/?g (1 EU/?g) as determined by LAL test.
Purity Greater than 90% as determined by reducing SDS-PAGE.
Description -
Reference -
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