タンパク質、抗体、アッセイキット
タンパク質カタログ
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- サプライヤー
- ELK Biotechnology
- カタログNo.
- EPT264
- 製品名称
- Recombinant Rhesus Macaque B7-H4 (C-Fc)
- タンパク質名
- 52.5 KDa
- Species
- -
- HOST
- B7S1; B7x; Vtcn1; B7h.5; B7-H4; B7H4T-cell costimulatory molecule B7x; B7S1VCTN1; B7XPRO1291; FLJ22418; Immune costimulatory protein B7-H4; Protein B7S1; T cell costimulatory molecule B7x; V-set domain containing T cell activation inhibitor 1; V-set domain-containing T-cell activation inhibitor 1
- 50ug: -
- お問い合わせ
Overview
| Synonyms | - |
|---|---|
| Characteristics | B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins.It is widely expressed, including in kidney, liver, lung, pancreas, placenta, prostate, spleen, testis and thymus. B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. It also involved in promoting epithelial cell transformation. |
| Endotoxin Level | Less than 0.1 ng/?g (1 EU/?g) as determined by LAL test. |
| Purity | Greater than 95% as determined by reducing SDS-PAGE. |
| Description | - |
| Reference | - |
| URL | - |

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