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- サプライヤー
- ELK Biotechnology
- カタログNo.
- EPT176
- 製品名称
- Recombinant Human FGFa (140AA)
- タンパク質名
- 16 KDa
- Species
- -
- HOST
- Fibroblast Growth Factor 1; FGF-1; Acidic Fibroblast Growth Factor; aFGF; Endothelial Cell Growth Factor; ECGFHeparin-Binding Growth Factor 1; HBGF-1; FGF1; FGFA
- 10ug: -
- お問い合わせ
Overview
| Synonyms | - |
|---|---|
| Characteristics | FGF acidic, also known as ECGF, FGF-1and HBGF-1, is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. It is a mitogenic peptide that is produced by multiple cell types and stimulates the proliferation of cells of mesodermal, ectodermal, and endodermal origin. Its association with heparan sulfate is a prerequisite for activation of FGF receptors. Internalized FGF acidic migrates to the nucleus where it is phosphorylated by nuclear PKC delta, exported to the cytosol, dephosphorylated, and degraded. Intracellular FGF acidic inhibits p53 activity and proapoptotic signaling. |
| Endotoxin Level | Less than 0.1 ng/?g (1 EU/?g) as determined by LAL test. |
| Purity | Greater than 95% as determined by reducing SDS-PAGE. |
| Description | - |
| Reference | - |
| URL | - |
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