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バイオ製品Bio Products

タンパク質、抗体、アッセイキット

タンパク質カタログ

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サプライヤー
ELK Biotechnology
カタログNo.
EPT170
製品名称
Recombinant Mouse VEGF 164
タンパク質名
19.27 KDa
Species
-
HOST
Vascular endothelial growth factor A; VEGF-A; Vascular permeability factor; VPF; VEGFA; VEGFA164; VEGF164
10ug: -
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Overview

Synonyms -
Characteristics Mouse Vascular endothelial growth factor (VEGF or VEGF?A), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the PDGF/VEGF growth factor family that is characterized by a cystine knot structure formed by eight conserved cysteine residues. Alternately spliced isoforms of 120, 164 and 188 aa found in mouse. VEGF binds the type I transmembrane receptor tyrosine kinases VEGF R1 (also called Flt?1) and VEGF R2 (Flk?/KDR) on endothelial cells.Although affinity is highest for binding to VEGF R1, VEGF R2 appears to be the primary mediator of VEGF angiogenic activity. VEGF is required during embryogenesis to regulate the proliferation, migration, and survival of endothelial cells.It may play a role in increasing vascular permeability during lactation, when increased transport of molecules from the blood is required for efficient milk protein synthesis.
Endotoxin Level Less than 0.1 ng/?g (1 EU/?g) as determined by LAL test.
Purity Greater than 95% as determined by reducing SDS-PAGE.
Description -
Reference -
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