タンパク質、抗体、アッセイキット
タンパク質カタログ
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- サプライヤー
- ELK Biotechnology
- カタログNo.
- EPT141
- 製品名称
- Recombinant Human TRAIL
- タンパク質名
- 19.5 KDa
- Species
- -
- HOST
- Tumor Necrosis Factor Ligand Superfamily Member 10; Apo-2 Ligand; Apo-2L; TNF-Related Apoptosis-Inducing Ligand; Protein TRAIL; CD253; TNFSF10; APO2L; TRAIL
- 10ug: -
- お問い合わせ
Overview
| Synonyms | - |
|---|---|
| Characteristics | Human TNFSF10 is a type II transmembrane protein with an intracellular N-terminus and a ‘TNF homology domain’ (THD) at the extracellular C terminus. TNFSF10 can interact with several distinct receptors. Two of these receptors that belongs to TNFR superfamily, DR4 (TRAIL-R1) and DR5 (TRAIL-R2/TRICK2), are plasma membrane proteins containing intracellular death domains essential for activating apoptosis. TNFSF10 is promising for cancer therapy because it is cytotoxic and activates apoptosis in the majority of malignant cells, but not in normal cells. |
| Endotoxin Level | Less than 0.1 ng/?g (1 EU/?g) as determined by LAL test. |
| Purity | Greater than 95% as determined by reducing SDS-PAGE. |
| Description | - |
| Reference | - |
| URL | - |

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