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タンパク質カタログ
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- サプライヤー
- ELK Biotechnology
- カタログNo.
- EPT130
- 製品名称
- Recombinant Rat M-CSF
- タンパク質名
- 25.2 KDa
- Species
- -
- HOST
- Macrophage colony-stimulating factor 1; CSF-1; M-CSF; MCSF; CSF1
- 10ug: -
- お問い合わせ
Overview
| Synonyms | - |
|---|---|
| Characteristics | Rat Macrophage colony-stimulating factor 1(MCSF,CSF1) is a single-pass type I membrane cytokine. It is a hematopoietic growth factor that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. MCSF promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It is involved in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development which for normal male and female fertility. It promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. MCSF also plays a role in lipoprotein clearance. |
| Endotoxin Level | Less than 0.1 ng/?g (1 EU/?g) as determined by LAL test. |
| Purity | Greater than 95% as determined by reducing SDS-PAGE. |
| Description | - |
| Reference | - |
| URL | - |
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