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タンパク質カタログ
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- サプライヤー
- ELK Biotechnology
- カタログNo.
- EPT121
- 製品名称
- Recombinant Mouse HGF (C-6His)
- タンパク質名
- 53.5&26.9 KDa
- Species
- -
- HOST
- Hepatopoietin-A; Scatter factor; SF; deafness; autosomal recessive 39; DFNB39; F-TCF; hepatocyte growth factor
- 10ug: -
- お問い合わせ
Overview
| Synonyms | - |
|---|---|
| Characteristics | HGF, is a pleiotropic protein in the Plasminogen subfamily of S1 peptidases. Mouse HGF is secreted as an inactive 728 amino acid (aa) single chain propeptide. It is cleaved after the fourth Kringle domain by a serine protease to form bioactive disulfide-linked HGF with a 60?kDa alpha ?and 30 kDa beta ?chain. HGF binds heparan-sulfate proteoglycans and the widely expressed receptor tyrosine kinase, HGF R/c-MET. HGF regulates epithelial morphogenesis by inducing cell scattering and branching tubulogenesis. ?It can also alter epithelium morphology by the induction of nectin?1 alpha ?ectodomain shedding, an adhesion protein component of adherens junctions?. |
| Endotoxin Level | Less than 0.001 ng/?g (0.01 EU/?g) as determined by LAL test. |
| Purity | Greater than 95% as determined by reducing SDS-PAGE. |
| Description | - |
| Reference | - |
| URL | - |
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