Recombinant Human LR3-IGF-1 [EPT077] | ナミキ商事株式会社

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サプライヤー: ELK Biotechnology
カタログNo.: EPT077
製品名称: Recombinant Human LR3-IGF-1
タンパク質名: 9.1 KDa
Species: -
HOST: Insulin-Like Growth Factor I; IGF-I; Mechano Growth Factor; MGF; Somatomedin-C; IGF1; IBP1

Synonyms	-
Characteristics	Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contains the N- and C-terminal propeptide regions. Mature human IGF-I consisting of 70 amino acids has 94% identity with mouse IGF-I and exhibits cross-species activity. IGF-1 binds IGF-IR, IGF-IIR, and the insulin receptor and plays a key role in cell cycle progression, cell proliferation and tumor progression. IGF-1 expression is regulated by growth hormone. R3 IGF-1 is an 83 amino acid analog of IGF-1 comprising the complete human IGF-1 sequence with the substitution of an Arg (R) for the Glu(E) at position three, hence R3, and a 13 amino acid extension peptide at the N terminus. R3 IGF-1 has been produced with the purpose of increasing biological activity. R3 IGF-1 is significantly more potent than human IGF-I in vitro.
Endotoxin Level	Less than 0.05 ng/?g (0.5 EU/?g) as determined by LAL test.
Purity	Greater than 95% as determined by reducing SDS-PAGE.
Description	-
Reference	-
URL	-

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