Recombinant Human B7-1 (C-6His) [EPT046] | ナミキ商事株式会社

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サプライヤー: ELK Biotechnology
カタログNo.: EPT046
製品名称: Recombinant Human B7-1 (C-6His)
タンパク質名: 24.7 KDa
Species: -
HOST: CD80; Activation B7-1 antigen; B7; BB1; CD28LG1; CD28LGB7-1 antigen; T-lymphocyte activation antigen CD80

Synonyms	-
Characteristics	Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of T cells. It is the ligand for two different proteins on the T cell surface: CD28 and CTLA-4. Studies have shown that CTLA-4 binds mostly to CD80. The structure presents two extracellular domains: a membrane distal variable-like domain (IgV) and a membrane proximal Ig constant-like domain (IgC) along with an intracellular domain. Both IgV and IgC consist of anti-parallel beta sandwiches joined by a short linker region. CD80 is mostly expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells.
Endotoxin Level	Less than 0.1 ng/?g (1 EU/?g) as determined by LAL test.
Purity	Greater than 95% as determined by reducing SDS-PAGE.
Description	-
Reference	-
URL	-

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