Recombinant Mouse IL-4 [EPT035] | ナミキ商事株式会社

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サプライヤー: ELK Biotechnology
カタログNo.: EPT035
製品名称: Recombinant Mouse IL-4
タンパク質名: 13.4 KDa
Species: -
HOST: Interleukin-4; B-cell IgG differentiation factor; B-cell growth factor 1; B-cell stimulatory factor 1; IGG1 induction factor; Lymphocyte stimulatory factor 1; IL-4; BSF-1

Synonyms	-
Characteristics	Mouse Interleukin-4(IL-4) is a monomeric, Th2 cytokine that shows pleiotropic effects during immune responses. It is a glycosylated polypeptide that contains three intrachain disulfide bridges and adopts a bundled four α?helix structure. IL?4 exerts its effects through two receptor complexes, Participates in at least several B-cell activation processes as well as of other cell types. IL?4 is primarily expressed by Th2?biased CD4+T cells, mast cells, basophils, and eosinophils. It promotes cell proliferation, survival, and immunoglobulin class switch to IgG1 and IgE in mouse B cells, acquisition of the Th2 phenotype by na?ve CD4+T cells, priming and chemotaxis of mast cells, eosinophils, and basophils, and the proliferation and activation of epithelial cells. IL?4 plays a dominant role in the development of allergic inflammation and asthma. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.
Endotoxin Level	Less than 0.001 ng/?g (0.01 EU/?g) as determined by LAL test.
Purity	Greater than 95% as determined by reducing SDS-PAGE.
Description	-
Reference	-
URL	-

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