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タンパク質、抗体、アッセイキット

タンパク質カタログ

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サプライヤー
ELK Biotechnology
カタログNo.
EPT012
製品名称
Recombinant Human IL-15
タンパク質名
12.5 KDa
Species
-
HOST
Interleukin-15; IL-15; IL15
50ug: -
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Overview

Synonyms -
Characteristics Human Interleukin 15 (IL-15) is a cytokine that regulates T cell and natural killer cell activation and proliferation. IL-15 binds to the alpha subunit of the IL15 receptor (IL-15RA) with high affinity. IL-15 also binds to the beta and gamma chains of the IL-2 receptor, but not the alpha subunit of the IL2 receptor. IL-15 is structurally and functionally related to IL-2. Both cytokines share some subunits of receptors, allowing them to compete for and negatively regulate each other's activity. The number of CD8+ memory T cells is controlled by a balance between IL-15 and IL-2. Despite their many overlapping functional properties, IL-2 and IL-15 are, in fact, quite distinct players in the immune system. IL-15 is constitutively expressed by a wide variety of cell types and tissues, including monocytes, macrophages and DCs. Mature Human IL-15 shares 70% amino acid sequence identity with Mouse and Rat IL-15.
Endotoxin Level Less than 0.001 ng/?g (0.01 EU/?g) as determined by LAL test.
Purity Greater than 95% as determined by reducing SDS-PAGE.
Description -
Reference -
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