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タンパク質カタログ
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- サプライヤー
- AcroBioSystems
- カタログNo.
- ENN-V5243
- 製品名称
- pHERV-W Envelope protein, His Tag
- タンパク質名
- Envelope protein
- Species
- pHERV-W
- HOST
- HEK293
Overview
| Synonyms | - |
|---|---|
| Characteristics | This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 33.9 kDa. The protein migrates as 48-58 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Endotoxin Level | N/A |
| Purity | 90% |
| Description | Dengue virus envelope (E) glycoprotein is a class II fusion protein mediating viral attachment and entry. Organized as dimers on the virion surface, it binds host receptors and, upon endosomal acidification, undergoes dramatic conformational rearrangements to drive membrane fusion. Structurally, E comprises three domains (DI, DII, DIII), with DIII responsible for receptor recognition. Highly immunogenic, E elicits neutralizing antibodies and is the principal target for vaccine design and therapeutic antibody development, as inhibiting its fusogenic transition blocks dengue virus infection. |
| Reference | - |
| URL | https://www.acrobiosystems.com/products/protein/envelope-protein-pherv-w-enn-v5243 |
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