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タンパク質カタログ
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- サプライヤー
- AcroBioSystems
- カタログNo.
- EN1-H5143
- 製品名称
- Human ENO1 Protein, His Tag (HPLC verified)
- タンパク質名
- ENO1
- Species
- Human
- HOST
- E. coli
Overview
| Synonyms | - |
|---|---|
| Characteristics | This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 49.1 kDa. The protein migrates as 50-55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE). |
| Endotoxin Level | 1.0 EU per μg |
| Purity | 95% |
| Description | Enolase 1 (ENO1), also known as alpha?enolase, is a glycolytic enzyme that catalyzes the conversion of 2?phosphoglycerate to phosphoenolpyruvate. It is ubiquitously expressed and accounts for the majority of cytosolic enolase activity. Beyond its metabolic role, ENO1 is a multifunctional “moonlighting” protein: on the cell surface it acts as a plasminogen receptor promoting extracellular matrix degradation and tumor invasion, while a nuclear isoform (MBP?1) binds the c?MYC promoter and regulates transcription. Overexpression of ENO1 has been linked to cancer progression, autoimmune diseases, and neurodegeneration, making it both a biomarker and a potential therapeutic target. |
| Reference | 1532 |
| URL | https://www.acrobiosystems.com/products/protein/eno1-human-en1-h5143 |
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