リコンビナントタンパク質
ACROBiosystems社 プロダクトリスト:Recombinant Protein
- サプライヤー
- AcroBioSystems
- カタログNo.
- EM2-H5142
- 製品名称
- Human AIMP1 / EMAP2 / SCYE1 Protein, His Tag
- タンパク質名
- AIMP1
- Species
- Human
- HOST
- E. coli
Overview
Synonyms | - |
---|---|
Characteristics | This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 35.2 kDa. The protein migrates as 36 kDa under reducing (R) condition (SDS-PAGE). |
Endotoxin Level | 1.0 EU per μg |
Purity | 95% |
Description | Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (AIMP1) is also known as multisynthase complex auxiliary component p43 and endothelial monocyte-activating polypeptide II (EMAP-II). AIMP1 is a cytokine that may be induced by apoptosis and is also released from professional antigen-presenting cells such as dendritic cells. The release of AIMP1 renders the tumor-associated vasculature sensitive to tumor necrosis factor. Furthermore, AIMP1 binds tRNA and stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. This protein possesses inflammatory cytokine activity. Also, AIMP1 negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation. |
Reference | - |
URL | https://www.acrobiosystems.com/P2104-Human-AIMP1--EMAP2--SCYE1-Protein-His-Tag.html |