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- サプライヤー
- AcroBioSystems
- カタログNo.
- DR2-H52D3
- 製品名称
- Human DRD2 Protein, Flag,His Tag (Detergent)
- タンパク質名
- DRD2
- Species
- Human
- HOST
- HEK293
Overview
| Synonyms | - |
|---|---|
| Characteristics | This protein carries a flag tag at the N-terminus and a polyhistidine tag at the C-terminus. The protein has a calculated MW of 48.3 kDa. |
| Endotoxin Level | 1.0 EU per μg |
| Purity | 90% |
| Description | Dopamine receptor D2 (DRD2) is G protein-coupled receptor (GPCR) that belong to the D2-like dopamine receptor family, couple to Gi to reduce adenylyl cyclase. DRD2s are expressed in different neuronal cell types within the striatum, dopamine binding leads to the inhibition of dopaminergic synaptic transmission. Altered expression level and function of DRD2s are observed in Parkinson's disease, making DRD2 one of the most common therapeutic targets for Parkinson's disease. DRD2 agonists can reduce the side effects of L-DOPA and enhance the therapeutic effect. |
| Reference | - |
| URL | https://www.acrobiosystems.com/products/protein/drd2-human-dr2-h52d3 |
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