タンパク質、抗体、アッセイキット
タンパク質カタログ
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- サプライヤー
- AcroBioSystems
- カタログNo.
- DDE-A51H3
- 製品名称
- Aspergillus fumigatus Dihydroorotate Dehydrogenase Protein, His Tag
- タンパク質名
- Dihydroorotate Dehydrogenase
- Species
- Aspergillus fumigatus
- HOST
- E. coli
Overview
| Synonyms | - |
|---|---|
| Characteristics | This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 49.5 kDa. The protein migrates as 55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE). |
| Endotoxin Level | N/A |
| Purity | 90% |
| Description | Aspergillus fumigatus dihydroorotate dehydrogenase (DHODH) is an essential mitochondrial enzyme in the de novo pyrimidine biosynthesis pathway, required for fungal DNA and RNA synthesis. Because A. fumigatus relies on DHODH for growth and survival, the enzyme has emerged as a validated antifungal drug target, exemplified by inhibitors such as olorofim |
| Reference | 1409 |
| URL | https://www.acrobiosystems.com/products/protein/dihydroorotate-dehydrogenase-aspergillus-fumigatus-dde-a51h3 |

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