Biotinylated Human CNTF R alpha Protein, His,Avitag? [CNR-H82Q3]

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Synonyms	-
Characteristics	This protein carries a polyhistidine tag at the N-terminus, followed by an Avi tag (Avitag?). The protein has a calculated MW of 39.8 kDa. The protein migrates as 53-63 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	N/A
Purity	90%
Description	CNTF receptor alpha (CNTFR) is a specialized protein primarily expressed in the nervous system and skeletal muscle. Unlike many receptors, it lacks a transmembrane domain and anchors to the cell surface via a GPI linkage. It functions as a crucial signaling component that binds Ciliary Neurotrophic Factor, subsequently recruiting gp130 and LIFR to initiate the JAK/STAT pathway. This process is vital for promoting neuronal survival, guiding motor neuron development, and regulating muscle regeneration.
Reference	1284
URL	https://www.acrobiosystems.com/products/protein/cntf-r-alpha-human-cnr-h82q3

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