Biotinylated Human CLEC4C / BDCA2 Protein, Avitag?,His Tag [CLC-H82Q3]

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Synonyms	-
Characteristics	This protein carries an Avi tag (Avitag?) at the N-terminus, followed by a polyhistidine tag. The protein has a calculated MW of 27.3 kDa. The protein migrates as 32-38 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	N/A
Purity	90%
Description	CLEC4C (C-type lectin domain family 4 member C), also known as BDCA2, CLECSF11, CLECSF7, DLEC and CD303. Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cell. Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man. Binds to serum IgG. Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium.
Reference	1266
URL	https://www.acrobiosystems.com/products/protein/clec4c-human-clc-h82q3

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